Curriculum Vitae

You can find my official CV here (updated 07-26-2018): Elias Oziolor_FullCV

Informal abbreviated resume

Education and Research

Postdoctoral fellow: 2017 to Present

Working with Dr. Andrew Whitehead at UC Davis.

  • We are exploring the impacts of population collapse in Pacific herring from Prince William Sound. A co-exposure of oil from Exxon-Valdez oil spill and viral hemorrhagic septicemia virus (VHCV) led to the collapse of this vital and economically important population. My main involvement is in two areas:
  1. Genomic resource development: Assembling the Pacific herring genome using 10x Chromium reads
  2. Population genomics We have genomic samples (n=1250) from Prince William Sound and two surrounding populations at four time points, including before and after the population collapse. I will be using time-series approaches to identify impacted genomic regions and begin to understand the demographic footprint of recent population collapse.
  3. Wetlab experiments Other than coding all day, I also get to help with some of our live dosing experiments with collaborators in Marrowstone USGS research station once in a while.

Doctoral fellow: 2012-2017

I got my PhD with Dr. Cole Matson at Baylor University.

  • In Cole’s lab I was able to sample from the great breadth of interests that he maintains in various aspects of Ecotoxicology. This resulted in a diverse set of projects, with one main theme: Understanding physiology and genomics of rapid evolution to anthropogenic contamination.

1. We identified an evolutionary adaptation through phenotypic divergence in populations of Gulf killifish(Fundulus grandis). Populations of these non-migratory fish that live in contaminated sites were 1000 times more resistant to developing cardiac deformities than proximate populations (100 miles), which lived in “clean” environment. You can see the paper here.

2. We identified that these populations were cross-resistant to multiple stressors, including pesticides and oxidative stress. Strangely enough, they do have higher resting metabolism. See paper here.

3. We performed a meta-analysis to see how frequently do we see such events and whether regulatory guidelines protect species from evolutionary events. The outcome resulted in important recommendations for evolutionary toxicology measurements of selective pressure, which prevent direct comparison to regulatory guidelines. See paper here.

4. So we decided to ourselves measure comprehensively the contaminants that imposed selective pressure on these populations. We identified a cline of chemical contamination throughout galveston bay among three matrices (sediment, fish, water). See paper here.

5. While looking at these incredible fish as a model organisms, we developed a fluorometric assay to measure activity of an enzyme commonly associated with exposure to pharmaceuticals. See paper here. And it also looks pretty cool.

6. And additionally we found a mechanistic explanation for induced tolerance to contaminants when individuals are pre-exposed to sub-lethal levels. Originally this phenomenon was seen in frogs, but with no mechanistic explanation. We were able to link AHR upregulation, leading to higher rate of biotransformation to the higher tolerance in developing individuals post early exposure. See paper here

Teaching experience

Data science

  • In July of 2018 I was a teaching assistant for the Data Intensive Biology Summer Institute or DIBSI at University of California at Davis. In addition to aiding students with general questions about transcriptome assembly and differential gene expression, I led a workshop on population genomics

  • In November of 2018, I am leading a workshop at the Society of Environmental Toxicology and Chemistry (SETAC). It will cover de novo assembly and differential expression analysis.
  • As of May 2018, I am a certified Data Carpentry instructor.

Environmental Science

  • I served as an instructor of record on the course Exploring Environmental Issues at Baylor University
  • As teaching assistant at Baylor, I was part of a diverse set of courses.
  • Without playing favorites, the course that I taught most frequently was Field methods. This was a class that the appropriate methods for air, water, soil, macroinvertebrate and fish assessments by the Texas Commissions on Environmental Quality (state version of the EPA). This involved 4 hours of field work weekly, followed by weekly full lab reports. A fantastic class that I would teach again in a heartbeat.

  • In addition I was a teaching assistant for Introduction to Biology lab, Introduction to Environmental Science Lab and Marine Environments lab.

Toxicology

  • I guest lectured at various courses on topics of ecotoxicology, evolutionary toxicology, genotoxicity and biochemistry.
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